QKI anticorps (AA 1-341)

N° du produit ABIN7166001

Détail du produit anti-QKI anticorps

Antigène: QKI (Protein Quaking (QKI))

Épitope: AA 1-341

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QKI est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Protein quaking protein (1-341AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur QKI

Antigène: QKI (Protein Quaking (QKI))

Autre désignation: QKI (QKI Produits)

Synonymes: anticorps Hqk, anticorps QK, anticorps QK1, anticorps QK3, anticorps hqkI, anticorps 1110003F05Rik, anticorps 1500005P18, anticorps QkI, anticorps l(17)-1Wis, anticorps l17Wis1, anticorps Qki, anticorps CQKI, anticorps QKI-5, anticorps PqkI, anticorps BqkI, anticorps qk, anticorps qk1, anticorps quaking, anticorps Xqua, anticorps qki, anticorps EQKI, anticorps EqkI, anticorps QKI, KH domain containing RNA binding, anticorps quaking, anticorps QKI, KH domain containing, RNA binding S homeolog, anticorps QKI, KH domain containing, RNA binding L homeolog, anticorps QKI, anticorps Qk, anticorps qki.S, anticorps qki.L, anticorps Qki

Sujet:

Background: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5\\\'-NACUAAY-N(1,20)-UAAY-3\\\' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).

Aliases: DKFZp586I0923 antibody, HKQ antibody, Homolog of mouse quaking QKI KH domain RNA binding protein antibody, Hqk antibody, HQK1 antibody, HqkI antibody, OTTHUMP00000017581 antibody, OTTHUMP00000017582 antibody, OTTHUMP00000017583 antibody, Protein quaking antibody, QK antibody, QK1 antibody, QK3 antibody, QKI antibody, QKI_HUMAN antibody, QKI1 antibody, Quaking homolog antibody, Quaking homolog KH domain RNA binding antibody, Quaking homolog KH domain RNA binding mouse antibody, Quaking isoform 1 antibody, Quaking protein antibody, RNA binding protein HQK antibody

UniProt: Q96PU8