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SBNO2 anticorps (AA 6-146) (Biotin)

SBNO2 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7166167
  • Antigène Voir toutes SBNO2 Anticorps
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Épitope
    AA 6-146
    Reactivité
    Humain
    Hôte
    • 4
    Lapin
    Clonalité
    • 4
    Polyclonal
    Conjugué
    • 2
    • 1
    • 1
    Cet anticorp SBNO2 est conjugé à/à la Biotin
    Application
    • 3
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
    Isotype
    IgG
    Top Product
    Discover our top product SBNO2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
    Autre désignation
    SBNO2 (SBNO2 Produits)
    Synonymes
    anticorps KIAA0963, anticorps SNO, anticorps STNO, anticorps BC019206, anticorps F730040C21, anticorps Sno, anticorps Stno, anticorps strawberry notch homolog 2, anticorps strawberry notch homolog 2 (Drosophila), anticorps SBNO2, anticorps Sbno2
    Sujet

    Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

    Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody

    UniProt
    Q9Y2G9
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