SBNO2 anticorps (AA 6-146) (Biotin)

N° du produit ABIN7166167

Détail du produit anti-SBNO2 anticorps (Biotin)

Antigène: SBNO2 (Strawberry Notch Homolog 2 (SBNO2))

Épitope: AA 6-146

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SBNO2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SBNO2

Antigène: SBNO2 (Strawberry Notch Homolog 2 (SBNO2))

Autre désignation: SBNO2 (SBNO2 Produits)

Synonymes: anticorps KIAA0963, anticorps SNO, anticorps STNO, anticorps BC019206, anticorps F730040C21, anticorps Sno, anticorps Stno, anticorps strawberry notch homolog 2, anticorps strawberry notch homolog 2 (Drosophila), anticorps SBNO2, anticorps Sbno2

Sujet:

Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody

UniProt: Q9Y2G9