ROS1 anticorps (AA 79-248)
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- Antigène Voir toutes ROS1 Anticorps
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Épitope
- AA 79-248
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ROS1 est non-conjugé
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Application
- ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Proto-oncogene tyrosine-protein kinase ROS protein (79-248AA)
- Isotype
- IgG
- Top Product
- Discover our top product ROS1 Anticorps primaire
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- Indications d'application
- Recommended dilution: IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Autre désignation
- ROS1 (ROS1 Produits)
- Synonymes
- anticorps MCF3, anticorps ROS, anticorps c-ros-1, anticorps ROS1C, anticorps Ros-1, anticorps c-ros, anticorps ROS proto-oncogene 1, receptor tyrosine kinase, anticorps ROS proto-oncogene 1 , receptor tyrosine kinase, anticorps Ros1 proto-oncogene, anticorps ROS1, anticorps Ros1
- Sujet
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Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
Aliases: c ros 1 antibody, c ros antibody, c ros oncogene 1 receptor tyrosine kinase antibody, c Ros receptor tyrosine kinase antibody, c ros1 antibody, MCF 3 antibody, MCF3 antibody, Oncogene ROS antibody, OTTHUMP00000017814 antibody, OTTHUMP00000017815 antibody, OTTHUMP00000040389 antibody, Proto oncogene c ros 1 protein antibody, Proto oncogene c Ros antibody, Proto oncogene tyrosine protein kinase ROS antibody, Proto oncogene tyrosine protein kinase ROS precursor antibody, Proto-oncogene c-Ros-1 antibody, Proto-oncogene tyrosine-protein kinase ROS antibody, Receptor tyrosine kinase c ros oncogene 1 antibody, Ros 1 antibody, ROS 1C antibody, ROS antibody, ROS proto oncogene 1 , receptor tyrosine kinase antibody, ROS_HUMAN antibody, ROS1 antibody, ROS1C antibody, Transmembrane tyrosine specific protein kinase antibody, v ros avian UR2 sarcoma virus oncogene homolog 1 antibody, v ros UR2 sarcoma virus oncogene homolog 1 antibody
- UniProt
- P08922
- Pathways
- Signalisation RTK
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