PYHIN1 anticorps (AA 1-245)

N° du produit ABIN7166880

Détail du produit anti-PYHIN1 anticorps

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Épitope: AA 1-245

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYHIN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PYHIN1

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Autre désignation: PYHIN1 (PYHIN1 Produits)

Synonymes: anticorps IFIX, anticorps RP11-520H16.1, anticorps 4930422C14, anticorps AI447904, anticorps Ifi209, anticorps Ifix, anticorps pyrin and HIN domain family member 1, anticorps interferon activated gene 209, anticorps PYHIN1, anticorps Ifi209

Sujet:

Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.

Aliases: IFIX_HUMAN antibody, Interferon-inducible protein X antibody, Pyhin1 antibody, Pyrin and HIN domain-containing protein 1 antibody

UniProt: Q6K0P9