QTRT1 anticorps (Catalytic Subunit 1)

N° du produit ABIN7166918

Détail du produit anti-QTRT1 anticorps

Antigène: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Épitope: AA 211-403, Catalytic Subunit 1

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QTRT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur QTRT1

Antigène: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Autre désignation: QTRT1 (QTRT1 Produits)

Synonymes: anticorps CG4947, anticorps Dmel\\CG4947, anticorps TGT, anticorps tgt, anticorps zgc:66378, anticorps FP3235, anticorps TGUT, anticorps 2610028E17Rik, anticorps Tgt, anticorps Tgut, anticorps tRNA-guanine transglycosylase, anticorps queuine tRNA-ribosyltransferase 1 S homeolog, anticorps queuine tRNA-ribosyltransferase 1, anticorps queuine tRNA-ribosyltransferase catalytic subunit 1, anticorps Tgt, anticorps Olsu_0732, anticorps Palpr_1298, anticorps Riean_1227, anticorps Calni_1240, anticorps Ftrac_0312, anticorps Ocepr_1541, anticorps Sulku_0977, anticorps Tmar_0854, anticorps Bache_2323, anticorps Nitsa_1291, anticorps Isop_1657, anticorps Despr_0021, anticorps Pedsa_1842, anticorps Corgl_1148, anticorps Mahau_0921, anticorps Theth_0831, anticorps qtrt1.S, anticorps qtrt1, anticorps QTRT1, anticorps Qtrt1

Sujet:

Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\\\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\\\' of the ribose to form the product (By similarity).

Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

UniProt: Q9BXR0

Pathways: Ribonucleoside Biosynthetic Process