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QTRT1 anticorps (Catalytic Subunit 1)

QTRT1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7166918
  • Antigène Voir toutes QTRT1 Anticorps
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-403, Catalytic Subunit 1
    Reactivité
    • 35
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp QTRT1 est non-conjugé
    Application
    • 25
    • 17
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Autre désignation
    QTRT1 (QTRT1 Produits)
    Synonymes
    anticorps CG4947, anticorps Dmel\\CG4947, anticorps TGT, anticorps tgt, anticorps zgc:66378, anticorps FP3235, anticorps TGUT, anticorps 2610028E17Rik, anticorps Tgt, anticorps Tgut, anticorps tRNA-guanine transglycosylase, anticorps queuine tRNA-ribosyltransferase 1 S homeolog, anticorps queuine tRNA-ribosyltransferase 1, anticorps queuine tRNA-ribosyltransferase catalytic subunit 1, anticorps Tgt, anticorps Olsu_0732, anticorps Palpr_1298, anticorps Riean_1227, anticorps Calni_1240, anticorps Ftrac_0312, anticorps Ocepr_1541, anticorps Sulku_0977, anticorps Tmar_0854, anticorps Bache_2323, anticorps Nitsa_1291, anticorps Isop_1657, anticorps Despr_0021, anticorps Pedsa_1842, anticorps Corgl_1148, anticorps Mahau_0921, anticorps Theth_0831, anticorps qtrt1.S, anticorps qtrt1, anticorps QTRT1, anticorps Qtrt1
    Sujet

    Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\\\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\\\' of the ribose to form the product (By similarity).

    Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

    UniProt
    Q9BXR0
    Pathways
    Ribonucleoside Biosynthetic Process
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