R-Spondin 3 anticorps (AA 22-272)

N° du produit ABIN7166936

Détail du produit anti-R-Spondin 3 anticorps

Antigène: R-Spondin 3 (RSPO3)

Épitope: AA 22-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp R-Spondin 3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human R-spondin-3 protein (22-272AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur R-Spondin 3

Antigène: R-Spondin 3 (RSPO3)

Autre désignation: RSPO3 (RSPO3 Produits)

Synonymes: anticorps pwtsr, anticorps thsd2, anticorps cristin1, anticorps CRISTIN1, anticorps PWTSR, anticorps THSD2, anticorps RGD1563246, anticorps 2810459H04Rik, anticorps AW742308, anticorps Cristin1, anticorps Thsd2, anticorps R-spondin 3, anticorps rspo3, anticorps RSPO3, anticorps Rspo3

Sujet:

Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

Aliases: CRISTIN1 antibody, hPWTSR antibody, hRspo3 antibody, Protein with TSP type-1 repeat antibody, PWTSR antibody, R-spondin 3 homolog antibody, R-spondin-3 [Precursor] antibody, R-spondin-3 antibody, Roof plate specific spondin-3 antibody, Roof plate-specific spondin-3 antibody, RSPO3 antibody, RSPO3_HUMAN antibody, Thrombospondin type I domain containing 2 antibody, Thrombospondin type-1 domain-containing protein 2 antibody, THSD2 antibody

UniProt: Q9BXY4