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R-Spondin 3 anticorps (AA 22-272) (FITC)

RSPO3 Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7166938
  • Antigène Voir toutes R-Spondin 3 (RSPO3) Anticorps
    R-Spondin 3 (RSPO3)
    Épitope
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-272
    Reactivité
    • 23
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 18
    • 2
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 21
    • 4
    Polyclonal
    Conjugué
    • 20
    • 2
    • 2
    • 1
    Cet anticorp R-Spondin 3 est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human R-spondin-3 protein (22-272AA)
    Isotype
    IgG
    Top Product
    Discover our top product RSPO3 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    R-Spondin 3 (RSPO3)
    Autre désignation
    RSPO3 (RSPO3 Produits)
    Synonymes
    anticorps pwtsr, anticorps thsd2, anticorps cristin1, anticorps CRISTIN1, anticorps PWTSR, anticorps THSD2, anticorps RGD1563246, anticorps 2810459H04Rik, anticorps AW742308, anticorps Cristin1, anticorps Thsd2, anticorps R-spondin 3, anticorps rspo3, anticorps RSPO3, anticorps Rspo3
    Sujet

    Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

    Aliases: CRISTIN1 antibody, hPWTSR antibody, hRspo3 antibody, Protein with TSP type-1 repeat antibody, PWTSR antibody, R-spondin 3 homolog antibody, R-spondin-3 [Precursor] antibody, R-spondin-3 antibody, Roof plate specific spondin-3 antibody, Roof plate-specific spondin-3 antibody, RSPO3 antibody, RSPO3_HUMAN antibody, Thrombospondin type I domain containing 2 antibody, Thrombospondin type-1 domain-containing protein 2 antibody, THSD2 antibody

    UniProt
    Q9BXY4
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