RSAD2 anticorps (AA 42-361)

N° du produit ABIN7167058

Détail du produit anti-RSAD2 anticorps

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Épitope: AA 42-361

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSAD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Radical S-adenosyl methionine domain-containing protein 2 protein (42-361AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RSAD2

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Autre désignation: RSAD2 (RSAD2 Produits)

Synonymes: anticorps CIG6, anticorps RSAD2, anticorps 2510004L01Rik, anticorps cig33, anticorps cig5, anticorps vig1, anticorps Vig1, anticorps Best5, anticorps si:ch211-276e8.2, anticorps zgc:112342, anticorps viperin, anticorps rsad2, anticorps radical S-adenosyl methionine domain containing 2, anticorps viperin, anticorps RSAD2, anticorps Rsad2, anticorps rsad2, anticorps vig1

Sujet:

Background: Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63\\\'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.

Aliases: 2510004L01Rik antibody, cig 33 antibody, CIG 5 antibody, cig-33 antibody, CIG-5 antibody, CIG33 antibody, CIG5 antibody, Cytomegalovirus induced gene 5 protein antibody, Cytomegalovirus-induced gene 5 protein antibody, endoplasmic reticulum-associated antibody, interferon-inducible antibody, Radical S adenosyl methionine domain containing 2 antibody, Radical S-adenosyl methionine domain-containing protein 2 antibody, RSAD 2 antibody, Rsad2 antibody, RSAD2_HUMAN antibody, RSDA-2 antibody, VIG 1 antibody, vig1 antibody, Viperin antibody, Virus inhibitory protein antibody, virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody

UniProt: Q8WXG1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response