MAPKSP1 anticorps (AA 1-124)

N° du produit ABIN7167072

Détail du produit anti-MAPKSP1 anticorps

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Épitope: AA 1-124

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKSP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MAPKSP1

Antigène: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Autre désignation: LAMTOR3 (MAPKSP1 Produits)

Synonymes: anticorps MAPKSP1, anticorps MAP2K1IP1, anticorps MAPBP, anticorps MP1, anticorps PRO0633, anticorps Ragulator3, anticorps AW556229, anticorps Map2k1ip1, anticorps Mapbp, anticorps Mapksp1, anticorps Mp1, anticorps mapksp1, anticorps zgc:110207, anticorps late endosomal/lysosomal adaptor, MAPK and MTOR activator 3, anticorps LAMTOR3, anticorps Lamtor3, anticorps lamtor3

Sujet:

Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Aliases: LAMTOR3 antibody, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody, LTOR3_HUMAN antibody, MAP2K1IP1 antibody, MEK binding partner 1 antibody, MEK partner 1 antibody, MEK-binding partner 1 antibody, Mitogen activated protein kinase kinase 1 interacting protein 1 antibody, Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody, Mitogen-activated protein kinase scaffold protein 1 antibody, Mp1 antibody, Ragulator complex protein LAMTOR3 antibody

UniProt: Q9UHA4

Pathways: Signalisation PI3K-Akt