RanBP3 anticorps (AA 1-250)

N° du produit ABIN7167094

Détail du produit anti-RanBP3 anticorps

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RanBP3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ran-binding protein 3 protein (1-250AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RanBP3

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Autre désignation: RANBP3 (RANBP3 Produits)

Synonymes: anticorps 2610024N24Rik, anticorps AA408221, anticorps ranbp3, anticorps MGC79798, anticorps zgc:63485, anticorps RAN binding protein 3, anticorps RAN binding protein 3 L homeolog, anticorps RAN binding protein 3a, anticorps RANBP3, anticorps Ranbp3, anticorps ranbp3.L, anticorps ranbp3, anticorps ranbp3a

Sujet:

Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

Aliases: DKFZp586I1520 antibody, Ran binding protein 3 antibody, Ran-binding protein 3 antibody, RANB3_HUMAN antibody, RanBP3 antibody

UniProt: Q9H6Z4