RASSF5 anticorps (AA 1-265)

N° du produit ABIN7167138

Détail du produit anti-RASSF5 anticorps

Antigène: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Épitope: AA 1-265

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RASSF5

Antigène: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Autre désignation: RASSF5 (RASSF5 Produits)

Synonymes: anticorps Maxp1, anticorps NORE1, anticorps NORE1A, anticorps NORE1B, anticorps RAPL, anticorps RASSF3, anticorps 1300019G20Rik, anticorps AU042887, anticorps Nore1, anticorps Nore1A, anticorps Nore1B, anticorps Rapl, anticorps Ras association domain family member 5, anticorps Ras association (RalGDS/AF-6) domain family member 5, anticorps RASSF5, anticorps Rassf5

Sujet:

Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Aliases: Maxp 1 antibody, MAXP1 antibody, MGC10823 antibody, MGC17344 antibody, New ras effector 1 antibody, NORE 1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, Novel Ras effector 1 antibody, RAP1 Binding Protein antibody, RAPL antibody, Ras association (RalGDS/AF 6) domain family 5 antibody, Ras association (RalGDS/AF 6) domain family member 5 antibody, Ras association domain containing family protein 5 antibody, Ras association domain-containing protein 5 antibody, Ras effector like protein antibody, RASF5_HUMAN antibody, RASSF 3 antibody, RASSF 5 antibody, RASSF3 antibody, RASSF5 antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody, Tumor suppressor RASSF3 antibody

UniProt: Q8WWW0

Pathways: TCR Signaling