RRAGA anticorps (AA 1-247) (Biotin)

N° du produit ABIN7167206

Détail du produit anti-RRAGA anticorps (Biotin)

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Épitope: AA 1-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAGA est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RRAGA

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Autre désignation: RRAGA (RRAGA Produits)

Synonymes: anticorps FIP-1, anticorps FIP1, anticorps RAGA, anticorps 1300010C19Rik, anticorps AI255374, anticorps Raga, anticorps Ras related GTP binding A, anticorps Ras-related GTP binding A, anticorps RRAGA, anticorps Rraga

Sujet:

Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

UniProt: Q7L523