RAB17 anticorps (AA 1-212)

N° du produit ABIN7167233

Détail du produit anti-RAB17 anticorps

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Épitope: AA 1-212

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ras-related protein Rab-17 protein (1-212AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAB17

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Autre désignation: RAB17 (RAB17 Produits)

Synonymes: anticorps RAB17, anticorps AW413472, anticorps RGD1562478, anticorps rab17, anticorps RAB17, member RAS oncogene family, anticorps EDI_278050, anticorps EDI_260720, anticorps EDI_050010, anticorps RAB17, anticorps Rab17

Sujet:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Aliases: AW413472 antibody, FLJ12538 antibody, OTTHUMP00000164417 antibody, OTTHUMP00000202805 antibody, Rab 17 antibody, Rab17 antibody, RAB17 member RAS oncogene family antibody, RAB17_HUMAN antibody, Ras related protein Rab 17 antibody, Ras related protein Rab17 antibody, Ras-related protein Rab-17 antibody

UniProt: Q9H0T7