RAB23 anticorps (AA 18-234) (HRP)

N° du produit ABIN7167257

Détail du produit anti-RAB23 anticorps (HRP)

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Épitope: AA 18-234

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB23 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras-related protein Rab-23 protein (18-234aa)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAB23

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Autre désignation: RAB23 (RAB23 Produits)

Synonymes: anticorps MGC82152, anticorps hspc137, anticorps zgc:110261, anticorps AW545388, anticorps opb, anticorps opb2, anticorps HSPC137, anticorps Rab23-like, anticorps RAB23, member RAS oncogene family S homeolog, anticorps RAB23, member RAS oncogene family, anticorps ras-related protein Rab-23, anticorps rab23.S, anticorps RAB23, anticorps rab23, anticorps Rab23

Sujet:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Aliases: Ras-related protein Rab-23, RAB23

UniProt: Q9ULC3

Pathways: Tube Formation