RAB7B anticorps (AA 100-199) (Biotin)

N° du produit ABIN7167382

Détail du produit anti-RAB7B anticorps (Biotin)

Antigène: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Épitope: AA 100-199

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB7B est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras-related protein Rab-7b protein (100-199AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAB7B

Antigène: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Autre désignation: RAB7B (RAB7B Produits)

Synonymes: anticorps RGD1562617, anticorps RAB7B, anticorps RAB7, anticorps Rab7b, anticorps Rab7b, member RAS oncogene family, anticorps rab7B protein, anticorps RAB7B, member RAS oncogene family, anticorps RAB7B, member RAS oncogene family S homeolog, anticorps Rab7b, anticorps rab7B, anticorps RAB7B, anticorps rab7b.S, anticorps rab7b

Sujet:

Background: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

Aliases: MGC16212 antibody, MGC9726 antibody, RAB7 antibody, rab7B antibody, RAB7B, member RAS oncogene family antibody, RAB7B_HUMAN antibody, Ras related protein Rab 7b antibody, Ras-related protein Rab-7B antibody

UniProt: Q96AH8