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RAB7B anticorps (AA 100-199) (HRP)

RAB7B Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7167384
  • Antigène Voir toutes RAB7B Anticorps
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    AA 100-199
    Reactivité
    • 27
    • 2
    • 1
    Humain
    Hôte
    • 21
    • 6
    Lapin
    Clonalité
    • 24
    • 3
    Polyclonal
    Conjugué
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    Cet anticorp RAB7B est conjugé à/à la HRP
    Application
    • 24
    • 22
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Ras-related protein Rab-7b protein (100-199AA)
    Isotype
    IgG
    Top Product
    Discover our top product RAB7B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    Autre désignation
    RAB7B (RAB7B Produits)
    Synonymes
    anticorps RGD1562617, anticorps RAB7B, anticorps RAB7, anticorps Rab7b, anticorps Rab7b, member RAS oncogene family, anticorps rab7B protein, anticorps RAB7B, member RAS oncogene family, anticorps RAB7B, member RAS oncogene family S homeolog, anticorps Rab7b, anticorps rab7B, anticorps RAB7B, anticorps rab7b.S, anticorps rab7b
    Sujet

    Background: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

    Aliases: MGC16212 antibody, MGC9726 antibody, RAB7 antibody, rab7B antibody, RAB7B, member RAS oncogene family antibody, RAB7B_HUMAN antibody, Ras related protein Rab 7b antibody, Ras-related protein Rab-7B antibody

    UniProt
    Q96AH8
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