SYNGAP1 anticorps (AA 1161-1343) (HRP)

N° du produit ABIN7167412

Détail du produit anti-SYNGAP1 anticorps (HRP)

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Épitope: AA 1161-1343

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNGAP1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras/Rap GTPase-activating protein SynGAP protein (1161-1343AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SYNGAP1

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Autre désignation: SYNGAP1 (SYNGAP1 Produits)

Synonymes: anticorps SYNGAP1, anticorps Syngap, anticorps MRD5, anticorps RASA1, anticorps RASA5, anticorps SYNGAP, anticorps Gm1963, anticorps synaptic Ras GTPase activating protein 1, anticorps zinc finger and BTB domain containing 9, anticorps synaptic Ras GTPase activating protein 1 homolog (rat), anticorps SYNGAP1, anticorps ZBTB9, anticorps syngap1, anticorps Syngap1

Sujet:

Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

Aliases: DKFZp761G1421 antibody, KIAA1938 antibody, MRD5 antibody, Neuronal RasGAP antibody, OTTHUMP00000064825 antibody, p135 SynGAP antibody, Ras GTPase activating protein SynGAP antibody, Ras GTPase-activating protein SynGAP antibody, RASA 1 antibody, RASA 5 antibody, RASA1 antibody, RASA5 antibody, SYGP1_HUMAN antibody, Synaptic Ras GAP 1 antibody, Synaptic Ras GTPase activating protein 1 antibody, Synaptic Ras GTPase activating protein 1 homolog antibody, Synaptic Ras GTPase activating protein 135 kDa antibody, Synaptic Ras GTPase activating protein antibody, Synaptic Ras GTPase-activating protein 1 antibody, Synaptic Ras-GAP 1 antibody, SYNGAP 1 antibody, SYNGAP1 antibody

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity