RIPK3 anticorps (AA 1-518)
-
- Antigène Voir toutes RIPK3 Anticorps
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
-
Épitope
- AA 1-518
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RIPK3 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-518AA)
- Isotype
- IgG
- Top Product
- Discover our top product RIPK3 Anticorps primaire
-
-
- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:200-1:500,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Autre désignation
- RIPK3 (RIPK3 Produits)
- Sujet
-
Background: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Aliases: Receptor interacting protein 3 antibody, Receptor interacting serine threonine kinase 3 antibody, Receptor interacting serine/threonine protein kinase 3 antibody, Receptor-interacting protein 3 antibody, Receptor-interacting serine/threonine-protein kinase 3 antibody, RIP 3 antibody, RIP like protein kinase 3 antibody, RIP-3 antibody, RIP-like protein kinase 3 antibody, RIPK 3 antibody, RIPK3 antibody, RIPK3_HUMAN antibody
- UniProt
- Q9Y572
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
-