RIPK3 anticorps (AA 1-518)

N° du produit ABIN7167480

Détail du produit anti-RIPK3 anticorps

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Épitope: AA 1-518

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-518AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3 (RIPK3 Produits)

Sujet:

Background: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Aliases: Receptor interacting protein 3 antibody, Receptor interacting serine threonine kinase 3 antibody, Receptor interacting serine/threonine protein kinase 3 antibody, Receptor-interacting protein 3 antibody, Receptor-interacting serine/threonine-protein kinase 3 antibody, RIP 3 antibody, RIP like protein kinase 3 antibody, RIP-3 antibody, RIP-like protein kinase 3 antibody, RIPK 3 antibody, RIPK3 antibody, RIPK3_HUMAN antibody

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades