RTEL1 anticorps (AA 975-1219)

N° du produit ABIN7167648

Détail du produit anti-RTEL1 anticorps

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Épitope: AA 975-1219

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTEL1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Regulator of telomere elongation helicase 1 protein (975-1219AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RTEL1

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Autre désignation: RTEL1 (RTEL1 Produits)

Synonymes: anticorps F18B13.3, anticorps F18B13_3, anticorps C20orf41, anticorps DKCB5, anticorps NHL, anticorps RTEL, anticorps bK3184A7.3, anticorps AI451565, anticorps AW540478, anticorps Rtel, anticorps RGD1306721, anticorps zgc:113114, anticorps regulator of telomere elongation helicase 1, anticorps RAD3-like DNA-binding helicase protein, anticorps RTEL1, anticorps rtel1, anticorps AT1G79950, anticorps LOC100286037, anticorps Rtel1

Sujet:

Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Aliases: RTEL1 antibody, C20orf41 antibody, KIAA1088 antibody, NHLRegulator of telomere elongation helicase 1 antibody, EC 3.6.4.12 antibody, Novel helicase-like antibody

UniProt: Q9NZ71