ARHGEF5 anticorps (AA 433-507)

N° du produit ABIN7167986

Détail du produit anti-ARHGEF5 anticorps

Antigène: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Épitope: AA 433-507

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF5 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARHGEF5

Antigène: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Autre désignation: ARHGEF5 (ARHGEF5 Produits)

Synonymes: anticorps ARHGEF5, anticorps GEF5, anticorps P60, anticorps TIM, anticorps TIM1, anticorps 2210412D05Rik, anticorps AA717842, anticorps AW495314, anticorps Tim1, anticorps Rho guanine nucleotide exchange factor 5, anticorps rho guanine nucleotide exchange factor 5, anticorps Rho guanine nucleotide exchange factor (GEF) 5, anticorps ARHGEF5, anticorps LOC100414419, anticorps Arhgef5

Sujet:

Background: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).

Aliases: ARHG5_HUMAN antibody, ARHGEF 5 antibody, ARHGEF5 antibody, DKFZp686N1969 antibody, ephexin 3 antibody, Ephexin-3 antibody, GEF 5 antibody, GEF5 antibody, Guanine nucleotide regulatory protein TIM antibody, Oncogene TIM antibody, P60 antibody, p60 TIM antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, Rho guanine nucleotide exchange factor 5 antibody, TIM 1 antibody, TIM antibody, TIM1 antibody, Transforming immortalized mammary oncogene antibody

UniProt: Q12774