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ROCK1 anticorps (AA 405-668)

ROCK1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7167999
  • Antigène Voir toutes ROCK1 Anticorps
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    Épitope
    • 16
    • 16
    • 15
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 405-668
    Reactivité
    • 80
    • 58
    • 56
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 72
    • 9
    Lapin
    Clonalité
    • 62
    • 19
    Polyclonal
    Conjugué
    • 34
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ROCK1 est non-conjugé
    Application
    • 63
    • 27
    • 26
    • 19
    • 16
    • 13
    • 11
    • 10
    • 10
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Rho-associated protein kinase 1 protein (405-668AA)
    Isotype
    IgG
    Top Product
    Discover our top product ROCK1 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    Autre désignation
    ROCK1 (ROCK1 Produits)
    Synonymes
    anticorps LOC100229794, anticorps CG9774, anticorps DROK, anticorps DRhk, anticorps DRok, anticorps Dmel\\CG9774, anticorps Drok, anticorps ROCK, anticorps ROCK-1, anticorps ROCK1, anticorps ROK, anticorps ROKalpha/beta, anticorps Rhk, anticorps RhoK, anticorps Rock, anticorps Rok, anticorps dROK, anticorps dRok, anticorps drok, anticorps 1110055K06Rik, anticorps Rock-I, anticorps P160Rock, anticorps ROCK-I, anticorps P160ROCK, anticorps p160ROCK, anticorps Rho associated coiled-coil containing protein kinase 1, anticorps Rho kinase, anticorps Rho-associated coiled-coil containing protein kinase 1, anticorps Rho-associated, coiled-coil containing protein kinase 1, anticorps ROCK1, anticorps Rok, anticorps Rock1, anticorps rock1
    Sujet

    Background: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.

    Aliases: coiled-coil-containing protein kinase 1 antibody, coiled-coil-containing protein kinase I antibody, MGC131603 antibody, MGC43611 antibody, p160 Rhoassociated coiled coil-forming protein kinase antibody, p160 ROCK-1 antibody, p160 ROCK1 antibody, p160ROCK antibody, PRO0435 antibody, Renal carcinoma antigen NY REN 35 antibody, Renal carcinoma antigen NY-REN-35 antibody, Rho associated coiled coil containing protein kinase 1 antibody, Rho associated protein kinase 1 antibody, Rho kinase antibody, Rho-alpha kinase antibody, Rho-associated antibody, Rho-associated protein kinase 1 antibody, ROCK I antibody, ROCK-I antibody, ROCK1 antibody, ROCK1_HUMAN antibody, Rok antibody, rokalpha antibody

    UniProt
    Q13464
    Pathways
    Dynamique des Microtubules, Signalisation WNT, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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