RRM2B anticorps (AA 1-351)

N° du produit ABIN7168147

Détail du produit anti-RRM2B anticorps

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Épitope: AA 1-351

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RRM2B

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Autre désignation: RRM2B (RRM2B Produits)

Sujet:

Background: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.

Aliases: DKFZp686M05248 antibody, MGC102856 antibody, MGC42116 antibody, MTDPS8A antibody, MTDPS8B antibody, p53 inducible ribonucleotide reductase small subunit 2 homolog antibody, p53 inducible ribonucleotide reductase small subunit 2 like protein antibody, P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody, p53 R2 antibody, p53-inducible ribonucleotide reductase small subunit 2-like protein antibody, p53R2 antibody, Ribonucleoside diphosphate reductase M2 subunit B antibody, Ribonucleoside-diphosphate reductase subunit M2 B antibody, Ribonucleotide reductase M2 B (TP53 inducible) antibody, Ribonucleotide reductase M2 B antibody, Ribonucleotide reductase small subunit like 2 p53 inducible antibody, RIR2B_HUMAN antibody, RRM 2B antibody, RRM2B antibody, TP53 inducible ribonucleotide reductase M2 B antibody, TP53-inducible ribonucleotide reductase M2 B antibody

UniProt: Q7LG56

Pathways: Signalisation p53, Negative Regulation of intrinsic apoptotic Signaling