RNF11 anticorps (AA 1-154)
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- Antigène Voir toutes RNF11 Anticorps
- RNF11 (Ring Finger Protein 11 (RNF11))
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Épitope
- AA 1-154
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RNF11 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human RING finger protein 11 protein (1-154AA)
- Isotype
- IgG
- Top Product
- Discover our top product RNF11 Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- RNF11 (Ring Finger Protein 11 (RNF11))
- Autre désignation
- RNF11 (RNF11 Produits)
- Synonymes
- anticorps SID1669, anticorps Sid1669, anticorps rnf11, anticorps rnf11-a, anticorps zgc:114095, anticorps zgc:63861, anticorps ring finger protein 11, anticorps ring finger protein 11 L homeolog, anticorps ring finger protein 11b, anticorps ring finger protein 11a, anticorps RNF11, anticorps Rnf11, anticorps rnf11.L, anticorps rnf11b, anticorps rnf11a
- Sujet
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Background: Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates \\\'Lys-63\\\' polyubiquitin chains on RIPK1 and catalyzes the formation of \\\'Lys-48\\\'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.
Aliases: CGI 123 antibody, RING finger protein 11 antibody, RNF11 antibody, RNF11_HUMAN antibody, Sid 1669 antibody, SID1669 antibody
- UniProt
- Q9Y3C5
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