NAT1 anticorps (AA 909-1025) (Biotin)

N° du produit ABIN7168284

Détail du produit anti-NAT1 anticorps (Biotin)

Antigène: NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))

Épitope: AA 909-1025

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAT1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human RNA cytidine acetyltransferase protein (909-1025AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NAT1

Antigène: NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))

Autre désignation: NAT1 (NAT1 Produits)

Synonymes: anticorps AAC1, anticorps MNAT, anticorps NAT-1, anticorps NATI, anticorps Nat-1, anticorps Nat, anticorps NAT1, anticorps AT-I, anticorps N-acetyltransferase 1, anticorps N-acetyl transferase 1, anticorps N-acetyltransferase 1 (arylamine N-acetyltransferase), anticorps arylamine N-acetyltransferase 1-like, anticorps NAT1, anticorps Nat1, anticorps LOC101095575

Sujet:

Background: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003).

Aliases: ALP antibody, DKFZp434C116 antibody, FLJ10774 antibody, FLJ12179 antibody, FLJ23850 antibody, hALP antibody, KIAA1709 antibody, N acetyltransferase 10 antibody, N acetyltransferase 10 GCN5 related antibody, N acetyltransferase like antibody, N acetyltransferase like protein antibody, N-acetyltransferase 10 antibody, NAT10 antibody, NAT10_HUMAN antibody, NET43 antibody

UniProt: Q9H0A0