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RBM4 anticorps (AA 121-205) (Biotin)

RBM4 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7168346
  • Antigène Voir toutes RBM4 Anticorps
    RBM4 (RNA Binding Motif Protein 4 (RBM4))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-205
    Reactivité
    • 29
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 1
    Lapin
    Clonalité
    • 28
    • 1
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    Cet anticorp RBM4 est conjugé à/à la Biotin
    Application
    • 26
    • 20
    • 7
    • 5
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human RNA-binding protein 4 protein (121-205AA)
    Isotype
    IgG
    Top Product
    Discover our top product RBM4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RBM4 (RNA Binding Motif Protein 4 (RBM4))
    Autre désignation
    RBM4 (RBM4 Produits)
    Synonymes
    anticorps rbm4, anticorps rna-bp4, anticorps wu:fc31f07, anticorps wu:fc57h11, anticorps zgc:56302, anticorps LARK, anticorps RBM4A, anticorps ZCCHC21, anticorps ZCRB3A, anticorps 4921506I22Rik, anticorps Lark1, anticorps Mlark, anticorps Rbm4a, anticorps lark, anticorps Rbm4, anticorps RNA binding motif protein 4.1, anticorps RNA binding motif protein 4, anticorps RNA-binding protein 14, anticorps RNA-binding protein lark, anticorps rbm4.1, anticorps RBM4, anticorps LOC610648, anticorps Rbm4, anticorps LARK
    Sujet

    Background: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5\\\'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3\\\'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3\\\'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5\\\'-CGCGCG[GCA]-3\\\' motif in vitro.

    Aliases: dkfzp547k0918 antibody, hLark antibody, lark antibody, Lark homolog antibody, lark homologue antibody, mgc75138 antibody, RBM4 antibody, rbm4 lark antibody, RBM4_HUMAN antibody, RNA binding motif 4 antibody, RNA binding motif 4a antibody, RNA-binding motif protein 4 antibody, RNA-binding motif protein 4a antibody, RNA-binding protein 4 antibody

    UniProt
    Q9BWF3
    Pathways
    Regulation of Muscle Cell Differentiation, Photoperiodism
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