SENP6 anticorps (AA 1-270)

N° du produit ABIN7168841

Détail du produit anti-SENP6 anticorps

Antigène: SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP6 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sentrin-specific protease 6 protein (1-270AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SENP6

Antigène: SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

Autre désignation: SENP6 (SENP6 Produits)

Synonymes: anticorps SSP1, anticorps SUSP1, anticorps 2810017C20Rik, anticorps E130319N12Rik, anticorps Susp1, anticorps mKIAA0797, anticorps fc83h02, anticorps im:7148342, anticorps wu:fc83h02, anticorps zgc:171230, anticorps SUMO1/sentrin specific peptidase 6, anticorps SUMO/sentrin specific peptidase 6, anticorps SUMO1/sentrin specific peptidase 6a, anticorps SENP6, anticorps Senp6, anticorps senp6a

Sujet:

Background: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.

Aliases: 2810017C20Rik antibody, FLJ11355 antibody, FLJ11887 antibody, KIAA0389 antibody, KIAA0797 antibody, SENP 6 antibody, Senp6 antibody, SENP6_HUMAN antibody, Sentrin specific protease 6 antibody, Sentrin-specific protease 6 antibody, Sentrin/SUMO specific protease SENP6 antibody, Sentrin/SUMO-specific protease SENP6 antibody, SSP 1 antibody, SSP1 antibody, SUMO 1 specific protease 1 antibody, SUMO 1 specific protease antibody, SUMO-1-specific protease 1 antibody, SUMO1 specific protease 1 antibody, SUMO1 specific protease antibody, SUMO1/sentrin specific peptidase 6 antibody, SUSP 1 antibody, SUSP1 antibody

UniProt: Q9GZR1