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HTRA1 anticorps (AA 23-248) (HRP)

HTRA1 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7168919
  • Antigène Voir toutes HTRA1 Anticorps
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Épitope
    • 9
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-248
    Reactivité
    • 47
    • 14
    • 11
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 49
    • 1
    Lapin
    Clonalité
    • 50
    Polyclonal
    Conjugué
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp HTRA1 est conjugé à/à la HRP
    Application
    • 34
    • 25
    • 17
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Serine protease HTRA1 protein (23-248AA)
    Isotype
    IgG
    Top Product
    Discover our top product HTRA1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Autre désignation
    HTRA1 (HTRA1 Produits)
    Synonymes
    anticorps htra1, anticorps zgc:92029, anticorps zgc:172061, anticorps l56, anticorps htra, anticorps Xhtra1, anticorps prss11, anticorps MGC145723, anticorps ARMD7, anticorps CARASIL, anticorps HtrA, anticorps L56, anticorps ORF480, anticorps PRSS11, anticorps AI429470, anticorps HTRA, anticorps Prss11, anticorps RSPP11, anticorps HTRA1, anticorps HtrA serine peptidase 1a, anticorps HtrA serine peptidase 1, anticorps HtrA serine peptidase 1b, anticorps Serine protease HTRA1, anticorps HtrA serine peptidase 1 S homeolog, anticorps htra1a, anticorps HTRA1, anticorps htra1b, anticorps htra1, anticorps Htra1, anticorps htra1.S
    Sujet

    Background: Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.

    Aliases: ARMD7 antibody, CARASIL antibody, High-temperature requirement A serine peptidase 1 antibody, HtrA antibody, HtrA serine peptidase 1 antibody, HTRA1 antibody, HTRA1_HUMAN antibody, IGFBP5 protease antibody, L56 antibody, ORF480 antibody, Protease serine 11 (IGF binding) antibody, protease serine 11 antibody, PRSS11 antibody, Serine protease 11 antibody, Serine protease HTRA1 antibody, Serine protease HTRA1 precursor antibody

    UniProt
    Q92743
    Pathways
    Growth Factor Binding
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