PAK3 anticorps (AA 70-190)
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- Antigène Voir toutes PAK3 Anticorps
- PAK3
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Épitope
- AA 70-190
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)
- Isotype
- IgG
- Top Product
- Discover our top product PAK3 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- PAK3
- Autre désignation
- PAK3 (PAK3 Produits)
- Sujet
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Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody
- UniProt
- O75914
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