PIM3 anticorps (AA 278-326) (HRP)

N° du produit ABIN7169152

Détail du produit anti-PIM3 anticorps (HRP)

Antigène: PIM3 (Pim-3 Oncogene (PIM3))

Épitope: AA 278-326

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM3 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PIM3

Antigène: PIM3 (Pim-3 Oncogene (PIM3))

Autre désignation: PIM3 (PIM3 Produits)

Synonymes: anticorps pim1-a, anticorps pim-3, anticorps BC026639, anticorps Kid1, anticorps Serine/threonine-protein kinase Pim-3, anticorps Pim-3 proto-oncogene, serine/threonine kinase S homeolog, anticorps Pim-3 proto-oncogene, serine/threonine kinase, anticorps pim-3 oncogene, anticorps proviral integration site 3, anticorps pim3, anticorps pim3.S, anticorps PIM3, anticorps Pim3

Sujet:

Background: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.

Aliases: Kid 1 antibody, Kid1 antibody, Kinase induced by depolarization antibody, ONCOGENE PIM3 antibody, PIM 3 antibody, Pim 3 oncogene antibody, Pim-3 proto-oncogene, serine/threonine kinase antibody, PIM3 antibody, Pim3 oncogene antibody, PIM3_HUMAN antibody, Protein kinase Kid 1 antibody, Protein kinase Kid1 antibody, Serine/threonine kinase Pim 3 antibody, Serine/threonine kinase Pim3 antibody, Serine/threonine protein kinase Pim 3 antibody, Serine/threonine protein kinase Pim3 antibody, Serine/threonine-protein kinase Pim-3 antibody

UniProt: Q86V86

Pathways: Negative Regulation of Hormone Secretion