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ULK3 anticorps (AA 44-240)

ULK3 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7169213
  • Antigène Voir toutes ULK3 Anticorps
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Épitope
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-240
    Reactivité
    • 54
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 61
    • 7
    • 2
    Lapin
    Clonalité
    • 64
    • 6
    Polyclonal
    Conjugué
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ULK3 est non-conjugé
    Application
    • 62
    • 39
    • 10
    • 10
    • 9
    • 6
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Serine/threonine-protein kinase ULK3 protein (44-240AA)
    Isotype
    IgG
    Top Product
    Discover our top product ULK3 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Autre désignation
    ULK3 (ULK3 Produits)
    Synonymes
    anticorps zgc:162196, anticorps 1200015E14Rik, anticorps unc-51 like kinase 3, anticorps unc-51 like kinase 3 L homeolog, anticorps unc-51-like kinase 3, anticorps ULK3, anticorps ulk3, anticorps Ulk3, anticorps ulk3.L
    Sujet

    Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

    Aliases: DKFZP434C131 antibody, FLJ90566 antibody, Serine/threonine-protein kinase ULK3 antibody, Ulk3 antibody, ULK3_HUMAN antibody, unc 51 like kinase 3 (C. elegans) antibody, Unc-51-like kinase 3 antibody

    UniProt
    Q6PHR2
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