SIGMAR1 anticorps (AA 112-169)

N° du produit ABIN7169599

Détail du produit anti-SIGMAR1 anticorps

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Épitope: AA 112-169

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGMAR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sigma non-opioid intracellular receptor 1 protein (112-169AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SIGMAR1

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Autre désignation: SIGMAR1 (SIGMAR1 Produits)

Synonymes: anticorps ALS16, anticorps OPRS1, anticorps SIG-1R, anticorps SR-BP, anticorps SR-BP1, anticorps SRBP, anticorps sigma1R, anticorps AL024364, anticorps Oprs1, anticorps mSigmaR1, anticorps Sigma1R, anticorps oprs1, anticorps zgc:56378, anticorps sigma non-opioid intracellular receptor 1, anticorps sigma non-opioid intracellular receptor 1 L homeolog, anticorps SIGMAR1, anticorps Sigmar1, anticorps sigmar1.L, anticorps sigmar1

Sujet:

Background: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151). Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria (By similarity).

Aliases: Aging associated gene 8 protein antibody, Aging-associated gene 8 protein antibody, AL024364 antibody, hSigmaR1 antibody, mSigmaR1 antibody, opioid receptor, sigma 1 antibody, opioid receptor, sigma 1 isoform 1 antibody, RP23 167I12.6 antibody, SGMR1_HUMAN antibody, SIG 1R antibody, SIG-1R antibody, Sigma 1-type opioid receptor antibody, Sigma non-opioid intracellular receptor 1 antibody, sigma1 receptor antibody, Sigma1-receptor antibody, Sigma1R antibody, Sigmar1 antibody, SR BP antibody, SR-BP antibody, SR31747 binding protein antibody, SR31747-binding protein antibody, SRBP antibody

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interactome