STAM2 anticorps (AA 376-525)
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- Antigène Voir toutes STAM2 Anticorps
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
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Épitope
- AA 376-525
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAM2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA)
- Isotype
- IgG
- Top Product
- Discover our top product STAM2 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Autre désignation
- STAM2 (STAM2 Produits)
- Synonymes
- anticorps Hbp, anticorps STAM2A, anticorps STAM2B, anticorps 1200004O12Rik, anticorps 5730456G07Rik, anticorps BB145015, anticorps stam2, anticorps MGC52950, anticorps zgc:103628, anticorps signal transducing adaptor molecule 2, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, anticorps signal transducing adaptor molecule 2 S homeolog, anticorps STAM2, anticorps Stam2, anticorps stam2.S, anticorps stam2
- Sujet
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Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
Aliases: DKFZp564C047 antibody, Hbp antibody, Hrs-binding protein antibody, HSE1 homolog antibody, Signal transducing adapter molecule 2 antibody, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, Signal transducing adaptor molecule 2A antibody, Signal transducing adaptor molecule 2B antibody, Signal transducing adaptor molecule antibody, STAM like protein containing SH3 and ITAM domains 2 antibody, STAM-2 antibody, Stam2 antibody, STAM2_HUMAN antibody, STAM2A antibody, STAM2B antibody
- UniProt
- O75886
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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