SLC5A8 anticorps (AA 540-610) (Biotin)
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- Antigène Voir toutes SLC5A8 Anticorps
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
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Épitope
- AA 540-610
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC5A8 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Sodium-coupled monocarboxylate transporter 1 protein (540-610AA)
- Isotype
- IgG
- Top Product
- Discover our top product SLC5A8 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
- Autre désignation
- SLC5A8 (SLC5A8 Produits)
- Synonymes
- anticorps Ait, anticorps SMCT, anticorps SMCT1, anticorps AIT, anticorps RGD1564146, anticorps solute carrier family 5 (iodide transporter), member 8, anticorps solute carrier family 5 member 8, anticorps Slc5a8, anticorps SLC5A8
- Sujet
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Background: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
Aliases: AIT antibody, Apical iodide transporter antibody, Electrogenic sodium monocarboxylate cotransporter antibody, MGC125354 antibody, SC5A8_HUMAN antibody, SLC5A8 antibody, SMCT antibody, SMCT1 antibody, sodium coupled monocarboxylate transporter 1 antibody, Sodium iodide related cotransporter antibody, Sodium iodide-related cotransporter antibody, Sodium-coupled monocarboxylate transporter 1 antibody, solute carrier family 5 iodide transporter member 8 antibody, Solute carrier family 5 member 8 antibody
- UniProt
- Q8N695
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