SLC38A9 anticorps (AA 1-119) (HRP)
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- Antigène Voir toutes SLC38A9 Anticorps
- SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
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Épitope
- AA 1-119
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC38A9 est conjugé à/à la HRP
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
- Isotype
- IgG
- Top Product
- Discover our top product SLC38A9 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
- Autre désignation
- SLC38A9 (SLC38A9 Produits)
- Synonymes
- anticorps MGC81406, anticorps 4833412L08Rik, anticorps 6720411P22Rik, anticorps 9130023D20Rik, anticorps 9430067K09Rik, anticorps A730092C09, anticorps RGD1311881, anticorps solute carrier family 38 member 9, anticorps solute carrier family 38 member 9 L homeolog, anticorps solute carrier family 38, member 9, anticorps SLC38A9, anticorps slc38a9.L, anticorps slc38a9, anticorps Slc38a9
- Sujet
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Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody
- UniProt
- Q8NBW4
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