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SLC38A9 anticorps (AA 1-119) (HRP)

SLC38A9 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7169975
  • Antigène Voir toutes SLC38A9 Anticorps
    SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
    Épitope
    • 4
    • 1
    AA 1-119
    Reactivité
    • 5
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 5
    Lapin
    Clonalité
    • 5
    Polyclonal
    Conjugué
    • 2
    • 2
    • 1
    Cet anticorp SLC38A9 est conjugé à/à la HRP
    Application
    • 3
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
    Isotype
    IgG
    Top Product
    Discover our top product SLC38A9 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
    Autre désignation
    SLC38A9 (SLC38A9 Produits)
    Synonymes
    anticorps MGC81406, anticorps 4833412L08Rik, anticorps 6720411P22Rik, anticorps 9130023D20Rik, anticorps 9430067K09Rik, anticorps A730092C09, anticorps RGD1311881, anticorps solute carrier family 38 member 9, anticorps solute carrier family 38 member 9 L homeolog, anticorps solute carrier family 38, member 9, anticorps SLC38A9, anticorps slc38a9.L, anticorps slc38a9, anticorps Slc38a9
    Sujet

    Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).

    Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody

    UniProt
    Q8NBW4
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