SSTR2 anticorps (AA 304-369)

N° du produit ABIN7170309

Détail du produit anti-SSTR2 anticorps

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Épitope: AA 304-369

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSTR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Somatostatin receptor type 2 protein (304-369AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SSTR2

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Autre désignation: SSTR2 (SSTR2 Produits)

Synonymes: anticorps Smstr2, anticorps SSTR-2, anticorps Smstr-2, anticorps sst2, anticorps SS2R, anticorps SSTR2, anticorps MGC80373, anticorps somatostatin receptor 2, anticorps somatostatin receptor 2 L homeolog, anticorps SSTR2, anticorps Sstr2, anticorps sstr2.L

Sujet:

Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

Aliases: Somatostatin receptor type 2 antibody, SRIF-1 antibody, SRIF1 antibody, SS-2-R antibody, SS2-R antibody, SS2R antibody, SSR2_HUMAN antibody, SST2 antibody, SSTR2 antibody

UniProt: P30874