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SSTR2 anticorps (AA 304-369)

SSTR2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7170309
  • Antigène Voir toutes SSTR2 Anticorps
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Épitope
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 304-369
    Reactivité
    • 42
    • 25
    • 23
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 4
    Lapin
    Clonalité
    • 37
    • 4
    • 1
    Polyclonal
    Conjugué
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SSTR2 est non-conjugé
    Application
    • 19
    • 13
    • 12
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Somatostatin receptor type 2 protein (304-369AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Autre désignation
    SSTR2 (SSTR2 Produits)
    Synonymes
    anticorps Smstr2, anticorps SSTR-2, anticorps Smstr-2, anticorps sst2, anticorps SS2R, anticorps SSTR2, anticorps MGC80373, anticorps somatostatin receptor 2, anticorps somatostatin receptor 2 L homeolog, anticorps SSTR2, anticorps Sstr2, anticorps sstr2.L
    Sujet

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Aliases: Somatostatin receptor type 2 antibody, SRIF-1 antibody, SRIF1 antibody, SS-2-R antibody, SS2-R antibody, SS2R antibody, SSR2_HUMAN antibody, SST2 antibody, SSTR2 antibody

    UniProt
    P30874
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