SNX27 anticorps (AA 458-497)

N° du produit ABIN7170381

Détail du produit anti-SNX27 anticorps

Antigène: SNX27 (Sorting Nexin 27 (SNX27))

Épitope: AA 458-497

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX27 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sorting nexin-27 protein (458-497AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SNX27

Antigène: SNX27 (Sorting Nexin 27 (SNX27))

Autre désignation: SNX27 (SNX27 Produits)

Synonymes: anticorps MRT1, anticorps MY014, anticorps 5730552M22Rik, anticorps ESTM45, anticorps ESTM47, anticorps R75405, anticorps mKIAA0488, anticorps Mrt1, anticorps sorting nexin family member 27, anticorps SNX27, anticorps Snx27

Sujet:

Background: Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.

Aliases: KIAA0488 antibody, Methamphetamine responsive transcript 1 antibody, MGC126871 antibody, MGC126873 antibody, MGC20471 antibody, MRT1 antibody, MY014 antibody, OTTHUMP00000042487 antibody, RP11-98D18.12 antibody, SNX27 antibody, SNX27_HUMAN antibody, Sorting nexin family member 27 antibody, Sorting nexin-27 antibody

UniProt: Q96L92