SPOP-B anticorps (AA 48-374) (HRP)
-
- Antigène Voir toutes SPOP-B Anticorps
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
-
Épitope
- AA 48-374
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SPOP-B est conjugé à/à la HRP
-
Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Speckle-type POZ protein (48-374AA)
- Isotype
- IgG
- Top Product
- Discover our top product SPOP-B Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Autre désignation
- SPOP (SPOP-B Produits)
- Synonymes
- anticorps BTBD32, anticorps TEF2, anticorps AI315626, anticorps Pcif1, anticorps zgc:64140, anticorps spop, anticorps tef2, anticorps speckle type BTB/POZ protein, anticorps speckle-type POZ protein, anticorps speckle type POZ protein S homeolog, anticorps SPOP, anticorps Spop, anticorps spop, anticorps spop.S
- Sujet
-
Background: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
Aliases: BTBD32 antibody, HIB homolog 1 antibody, Roadkill homolog 1 antibody, Speckle type POZ protein antibody, Speckle-type POZ protein antibody, SPOP antibody, SPOP_HUMAN antibody, TEF 2 antibody, TEF2 antibody
- UniProt
- O43791
-