SPAG5 anticorps (AA 1-300)

N° du produit ABIN7170478

Détail du produit anti-SPAG5 anticorps

Antigène: SPAG5 (Sperm Associated Antigen 5 (SPAG5))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Sperm-associated antigen 5 protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SPAG5

Antigène: SPAG5 (Sperm Associated Antigen 5 (SPAG5))

Autre désignation: SPAG5 (SPAG5 Produits)

Synonymes: anticorps SPAG5, anticorps DEEPEST, anticorps MAP126, anticorps hMAP126, anticorps AI874642, anticorps D11Bhm180e, anticorps Deepest, anticorps Mastrin, anticorps S17, anticorps sperm associated antigen 5, anticorps sperm-associated antigen 5, anticorps SPAG5, anticorps LOC739263, anticorps Spag5

Sujet:

Background: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.

Aliases: Astrin antibody, Deepest antibody, hMAP 126 antibody, hMAP126 antibody, MAP 126 antibody, MAP126 antibody, Mitotic spindle associated protein antibody, Mitotic spindle associated protein p126 antibody, Mitotic spindle coiled coil related protein antibody, Mitotic spindle-associated protein p126 antibody, SPAG 5 antibody, SPAG5 antibody, SPAG5_HUMAN antibody, Sperm associated antigen 5 antibody, Sperm tail protein Spag 5 antibody, Sperm tail protein Spag5 antibody, Sperm-associated antigen 5 antibody

UniProt: Q96R06

Pathways: M Phase