SAMD8 anticorps (AA 1-152) (HRP)

N° du produit ABIN7170564

Détail du produit anti-SAMD8 anticorps (HRP)

Antigène: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Épitope: AA 1-152

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAMD8 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SAMD8

Antigène: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Autre désignation: SAMD8 (SAMD8 Produits)

Synonymes: anticorps CG32380, anticorps CG8572, anticorps CG8576, anticorps Css3beta, anticorps Dmel\\CG32380, anticorps dSMSr, anticorps dmSMSr, anticorps SMSr, anticorps 1110053F04Rik, anticorps 1700010P07Rik, anticorps CG32380 gene product from transcript CG32380-RA, anticorps sterile alpha motif domain containing 8, anticorps SMSr, anticorps SAMD8, anticorps samd8, anticorps Samd8

Sujet:

Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

Aliases: SAMD8Sphingomyelin synthase-related protein 1 antibody, SMSr antibody, EC 2.7.8.- antibody, Ceramide phosphoethanolamine synthase antibody, CPE synthase antibody, Sterile alpha motif domain-containing protein 8 antibody, SAM domain-containing protein 8 antibody

UniProt: Q96LT4