SKA3 anticorps (AA 101-195)

N° du produit ABIN7170595

Détail du produit anti-SKA3 anticorps

Antigène: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Épitope: AA 101-195

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKA3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SKA3

Antigène: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Autre désignation: SKA3 (SKA3 Produits)

Synonymes: anticorps C13orf3, anticorps RAMA1, anticorps RGD1307201, anticorps C12H13ORF3, anticorps fc23d11, anticorps si:rp71-68n21.13, anticorps wu:fc23d11, anticorps rama1, anticorps F630043A04Rik, anticorps spindle and kinetochore associated complex subunit 3, anticorps spindle and kinetochore associated complex subunit 3 L homeolog, anticorps SKA3, anticorps Ska3, anticorps ska3, anticorps ska3.L

Sujet:

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody

UniProt: Q8IX90