Spindlin 1 anticorps (AA 1-262)
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- Antigène Voir toutes Spindlin 1 (SPIN1) Anticorps
- Spindlin 1 (SPIN1)
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Épitope
- AA 1-262
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Spindlin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Spindlin-1 protein (1-262AA)
- Isotype
- IgG
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anti-Spindlin 1 (SPIN1) (AA 1-262) antibody
SPIN1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (N-Term) antibodySPIN1 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 3-100) antibodySPIN1 Reactivité: Humain ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 111-160) antibodySPIN1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 179-228) antibodySPIN1 Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Lapin, Poulet, Singe, Cobaye, Poisson zèbre (Danio rerio), Roussette (Chauve-souris), Xenopus laevis WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Middle Region) antibodySPIN1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio), Cheval WB Hôte: Lapin Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- Spindlin 1 (SPIN1)
- Autre désignation
- SPIN1 (SPIN1 Produits)
- Synonymes
- anticorps SPIN, anticorps AA553322, anticorps AA673430, anticorps Spin, anticorps spin, anticorps spindlin, anticorps MGC115436, anticorps Spindlin-1, anticorps DKFZp459K085, anticorps spindlin 1, anticorps spindlin 1 L homeolog, anticorps SPIN1, anticorps Spin1, anticorps spin1, anticorps spin1.L
- Sujet
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Background: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at \\\'Lys-4\\\' and asymmetrically dimethylated at \\\'Arg-8\\\' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
Aliases: OCR antibody, Ovarian cancer-related protein antibody, SPIN antibody, Spin1 antibody, SPIN1_HUMAN antibody, Spindlin-1 antibody
- UniProt
- Q9Y657
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