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SMC5 anticorps (AA 296-403) (HRP)

SMC5 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7170873
  • Antigène Voir toutes SMC5 Anticorps
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Épitope
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 296-403
    Reactivité
    • 34
    • 18
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 1
    • 1
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMC5 est conjugé à/à la HRP
    Application
    • 23
    • 13
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Structural maintenance of chromosomes protein 5 protein (296-403AA)
    Isotype
    IgG
    Top Product
    Discover our top product SMC5 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Autre désignation
    SMC5 (SMC5 Produits)
    Synonymes
    anticorps F1N13.60, anticorps F1N13_60, anticorps structural maintenance of chromosomes 5, anticorps SMC-5, anticorps SMC5L1, anticorps MLZ-453, anticorps Smc5l1, anticorps mKIAA0594, anticorps mSMC5, anticorps structural maintenance of chromosomes 5, anticorps structural maintenance of chromosomes 5 S homeolog, anticorps SMC5, anticorps smc5, anticorps Smc5, anticorps smc5.S
    Sujet

    Background: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).

    Aliases: SMC5 antibody, KIAA0594 antibody, SMC5L1 antibody, Structural maintenance of chromosomes protein 5 antibody, SMC protein 5 antibody, SMC-5 antibody, hSMC5 antibody

    UniProt
    Q8IY18
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