TPX2 anticorps (AA 160-320)
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- Antigène Voir toutes TPX2 Anticorps
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Épitope
- AA 160-320
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TPX2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Targeting protein for Xklp2 protein (160-320AA)
- Isotype
- IgG
- Top Product
- Discover our top product TPX2 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
- Autre désignation
- TPX2 (TPX2 Produits)
- Synonymes
- anticorps C20orf1, anticorps C20orf2, anticorps DIL-2, anticorps DIL2, anticorps FLS353, anticorps GD:C20orf1, anticorps HCA519, anticorps HCTP4, anticorps REPP86, anticorps p100, anticorps 2610005B21Rik, anticorps TPX2, anticorps dil-2, anticorps dil2, anticorps hctp4, anticorps repp86, anticorps tpx2, anticorps TPX2, microtubule nucleation factor, anticorps TPX2, microtubule-associated, anticorps TPX2, microtubule-associated, homolog (Xenopus laevis), anticorps TPX2, microtubule-associated S homeolog, anticorps TPX2, microtubule-associated L homeolog, anticorps TPX2, anticorps Tpx2, anticorps tpx2.S, anticorps tpx2.L
- Sujet
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Background: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at \\\'Thr-288\\\' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
Aliases: C20ORF1 antibody, C20orf2 antibody, Chromosome 20 Open Reading Frame 1 antibody, Differentially expressed in cancerous and non-cancerous lung cells 2 antibody, Differentially expressed in cancerous and noncancerous lung cells 2 antibody, Differentially expressed in lung cells 2 antibody, Differentially expressed in lung cells antibody, DIL 2 antibody, DIL-2 antibody, DIL2 antibody, FLS353 antibody, GD:C20orf1 antibody, HCA 519 antibody, HCA519 antibody, HCTP 4 antibody, HCTP4 antibody, Hepatocellular carcinoma associated antigen 519 antibody, Hepatocellular carcinoma-associated antigen 519 antibody, p100 antibody, Preferentially expressed in colorectal cancer antibody, Protein fls353 antibody, REPP 86 antibody, repp86 antibody, Restricted expression proliferation associated protein 100 antibody, Restricted expression proliferation-associated protein 100 antibody, Targeting protein for Xklp2 antibody, TPX 2 antibody, TPX2 antibody, TPX2 microtubule associated homolog antibody, TPX2 microtubule associated protein homolog antibody, TPX2 microtubule nucleation factor antibody, TPX2_HUMAN antibody
- UniProt
- Q9ULW0
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