TBC1D7 anticorps (AA 1-293)

N° du produit ABIN7171658

Détail du produit anti-TBC1D7 anticorps

Antigène: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Épitope: AA 1-293

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human TBC1 domain family member 7 protein (1-293AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TBC1D7

Antigène: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Autre désignation: TBC1D7 (TBC1D7 Produits)

Synonymes: anticorps PIG51, anticorps TBC7, anticorps dJ257A7.3, anticorps 2610009C09Rik, anticorps TBC1 domain family member 7, anticorps TBC1 domain family, member 7, anticorps TBC1D7, anticorps Tbc1d7

Sujet:

Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.

Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody

UniProt: Q9P0N9