TRF1 anticorps (AA 260-439)

N° du produit ABIN7171728

Détail du produit anti-TRF1 anticorps

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Épitope: AA 260-439

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Telomeric repeat-binding factor 1 protein (260-439AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRF1

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Autre désignation: TERF1 (TERF1 Produits)

Synonymes: anticorps PIN2, anticorps TRBF1, anticorps TRF, anticorps TRF1, anticorps hTRF1-AS, anticorps t-TRF1, anticorps wu:fb74c04, anticorps TERF1, anticorps DKFZp459A0713, anticorps Pin2, anticorps Trbf1, anticorps Trf1, anticorps terf1, anticorps trf1, anticorps telomeric repeat binding factor 1, anticorps telomeric repeat binding factor (NIMA-interacting) 1, anticorps telomeric repeat binding factor (NIMA-interacting) 1 L homeolog, anticorps TERF1, anticorps Terf1, anticorps terf1, anticorps Trf1, anticorps terf1.L

Sujet:

Background: Binds the telomeric double-stranded 5\\\'-TTAGGG-3\\\' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5\\\'-TTAGGG-3\\\' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

Aliases: hTRF1 AS antibody, NIMA interacting protein 2 antibody, NIMA-interacting protein 2 antibody, PIN 2 antibody, PIN2 antibody, t TRF1 antibody, Telomeric protein Pin2 antibody, Telomeric protein Pin2/TRF1 antibody, Telomeric repeat binding factor (NIMA interacting) 1 antibody, Telomeric repeat binding factor 1 antibody, Telomeric repeat binding protein 1 antibody, Telomeric repeat-binding factor 1 antibody, TERF 1 antibody, Terf1 antibody, TERF1_HUMAN antibody, TRBF 1 antibody, TRBF1 antibody, TRF 1 antibody, TRF antibody, TTAGGG repeat binding factor 1 antibody, TTAGGG repeat-binding factor 1 antibody

UniProt: P54274

Pathways: Cycle Cellulaire, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity