TPMT anticorps (AA 4-244)

N° du produit ABIN7171992

Détail du produit anti-TPMT anticorps

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Épitope: AA 4-244

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPMT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Thiopurine S-methyltransferase protein (4-244AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TPMT

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Autre désignation: TPMT (TPMT Produits)

Synonymes: anticorps MGC84277, anticorps AW106912, anticorps NHLRC1, anticorps thiopurine S-methyltransferase L homeolog, anticorps thiopurine S-methyltransferase, tandem duplicate 2, anticorps thiopurine S-methyltransferase TpmT, anticorps thiopurine S-methyltransferase, anticorps Thiopurine S-methyltransferase, anticorps thiopurine methyltransferase, anticorps tpmt.L, anticorps tpmt.2, anticorps tpmT, anticorps MCA0794, anticorps Pnap_4948, anticorps Hhal_1383, anticorps TK90_1044, anticorps Slit_1144, anticorps Tint_0842, anticorps Fbal_3334, anticorps Celly_3188, anticorps Weevi_1737, anticorps Psefu_2696, anticorps Metme_3860, anticorps Tpmt, anticorps TPMT

Sujet:

Background: TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Aliases: HGNC:12014 antibody, S adenosyl L methionine thiopurine S methyltransferase antibody, Thiopurine methyltransferase antibody, Thiopurine S methyltransferase antibody, Thiopurine S-methyltransferase antibody, TPMT antibody, TPMT_HUMAN antibody

UniProt: P51580