THOC6 anticorps (AA 56-315)

N° du produit ABIN7172063

Détail du produit anti-THOC6 anticorps

Antigène: THOC6 (THO Complex 6 Homolog (THOC6))

Épitope: AA 56-315

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THOC6 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human THO complex subunit 6 homolog protein (56-315AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur THOC6

Antigène: THOC6 (THO Complex 6 Homolog (THOC6))

Autre désignation: THOC6 (THOC6 Produits)

Synonymes: anticorps WDR58, anticorps fSAP35, anticorps F830014G06Rik, anticorps Wdr58, anticorps Pdrp, anticorps zgc:101618, anticorps thoc6, anticorps THO complex 6, anticorps THO complex 6 homolog (Drosophila), anticorps THO complex 6 L homeolog, anticorps THOC6, anticorps Thoc6, anticorps thoc6, anticorps thoc6.L

Sujet:

Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

Aliases: THOC6 antibody, WDR58 antibody, PSEC0006 antibody, THO complex subunit 6 homolog antibody, Functional spliceosome-associated protein 35 antibody, fSAP35 antibody, WD repeat-containing protein 58 antibody

UniProt: Q86W42