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TFEB anticorps (AA 1-476)

TFEB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7172536
  • Antigène Voir toutes TFEB Anticorps
    TFEB (Transcription Factor EB (TFEB))
    Épitope
    • 16
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-476
    Reactivité
    • 62
    • 30
    • 26
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 7
    • 1
    Lapin
    Clonalité
    • 55
    • 6
    Polyclonal
    Conjugué
    • 38
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TFEB est non-conjugé
    Application
    • 56
    • 31
    • 14
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Transcription factor EB protein (1-476AA)
    Isotype
    IgG
    Top Product
    Discover our top product TFEB Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    TFEB (Transcription Factor EB (TFEB))
    Autre désignation
    TFEB (TFEB Produits)
    Synonymes
    anticorps TFEB, anticorps tcfeb, anticorps MGC145796, anticorps alphatfeb, anticorps ALPHATFEB, anticorps BHLHE35, anticorps TCFEB, anticorps Tcfeb, anticorps bHLHe35, anticorps transcription factor EB, anticorps TFEB, anticorps tfeb, anticorps Tfeb
    Sujet

    Background: Transcription factor that specifically recognizes and binds E-box sequences (5\\\'-CANNTG-3\\\'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5\\\'-GTCACGTGAC-3\\\') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.

    Aliases: Alpha TFEB antibody, AlphaTFEB antibody, bHLHe35 antibody, Class E basic helix-loop-helix protein 35 antibody, T cell transcription factor EB antibody, TCFEB antibody, TFEB antibody, TFEB_HUMAN antibody, Transcription factor EB antibody

    UniProt
    P19484
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