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MAFB anticorps (AA 168-323) (Biotin)

MAFB Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7172579
  • Antigène Voir toutes MAFB Anticorps
    MAFB (Transcription Factor MafB (MAFB))
    Épitope
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-323
    Reactivité
    • 38
    • 14
    • 13
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 2
    Lapin
    Clonalité
    • 35
    • 3
    Polyclonal
    Conjugué
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAFB est conjugé à/à la Biotin
    Application
    • 29
    • 16
    • 14
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Transcription factor MafB protein (168-323AA)
    Isotype
    IgG
    Top Product
    Discover our top product MAFB Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MAFB (Transcription Factor MafB (MAFB))
    Autre désignation
    MAFB (MAFB Produits)
    Synonymes
    anticorps MAFB, anticorps krml, anticorps Maf-B, anticorps XMafB, anticorps kreisler, anticorps MGC108453, anticorps valentino, anticorps KRML, anticorps MCTO, anticorps Krml, anticorps b-maf, anticorps kr, anticorps mafb, anticorps val, anticorps wu:fc22d11, anticorps wu:fj82a09, anticorps Kreisler, anticorps Krml1, anticorps MAF bZIP transcription factor B, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian), anticorps MAFB, anticorps mafb, anticorps mafb.S, anticorps Mafb, anticorps mafba
    Sujet

    Background: Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

    Aliases: Kreisler antibody, Kreisler (mouse) maf related leucine zipper homolog antibody, Kreisler maf related leucine zipper homolog antibody, KRML antibody, MAF bZIP transcription factor B antibody, Maf-B antibody, Mafb antibody, MAFB/Kreisler basic region/leucine zipper transcription factor antibody, MAFB_HUMAN antibody, MGC43127 antibody, Segmentation protein KR antibody, Transcription factor MafB antibody, V maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) antibody, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B antibody

    UniProt
    Q9Y5Q3
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