RFX3 anticorps (AA 201-413)

N° du produit ABIN7172598

Détail du produit anti-RFX3 anticorps

Antigène: RFX3 (Regulatory Factor X 3 (RFX3))

Épitope: AA 201-413

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFX3 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transcription factor RFX3 protein (201-413AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RFX3

Antigène: RFX3 (Regulatory Factor X 3 (RFX3))

Autre désignation: RFX3 (RFX3 Produits)

Sujet:

Background: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.

Aliases: bA32F11.1 antibody, DNA binding protein RFX3 antibody, Regulatory factor X 3 antibody, Regulatory factor X, 3 (influences HLA class II expression) antibody, RFX3 antibody, RFX3_HUMAN antibody, Transcription factor RFX3 antibody

UniProt: P48380